History

  • Floaters
  • Visual loss
  • CMV / toxoplasmosis is AIDS-defining

Relevant physical signs

  • Fundoscopy
    • CMV
      • Diffuse scarring
      • Pizza pie appearance
      • Retinal opacification
      • Perivascular sheathing
    • Congenital toxoplasmosis
      • Punched-out macula scar

Causes

  • Infection
    • Toxoplasmosis
    • Others: syphilis, Epstein-Barr virus, tuberculosis, Bartonella
    • Rubella
    • Cytomegalovirus
    • Herpes simplex, herpes zoster
  • Inflammatory
    • Sarcoidosis
    • Bechet’s syndrome

Treatment

  • Intravitreal ganciclovir (CMV)