The component represents a source of concentrated FVIII:C, and von Willebrand factor, fibrinogen, FXIII and fibronectin from a unit of fresh frozen plasma.
Contains less than 1 × 106 leucocytes per component
Donations where bleed time >15min are not suitable for production of plasma for clinical use
Produced by thawing a single donation of FFP at 4±2°C
Plasma should be from male donors to reduce TRALI risk.
Storage:
Rapidly frozen to <-25°C within 2hrs of preparation.
Store for maximum of 36 months
Thawing:
Waterbath within vacuum-sealed overwrap plastic bag at 37° (between 33-37°C ok)
Equipment should be cleaned daily
Once thawed, use within 4 hours and do not re-freeze.
Component for QA assessment of FVIII should be from an equal mix of group O and non-O donations due to varying levels of FVIII between blood groups.
Cryoprecipitated, Pooled, Leukocyte-Depleted
As above, but pool five single cryoprecipitate components
Leave A Comment