FRCPath Haematology Part 2: Morphology RBC Morphology Overview Pappenheimer Bodies

Pappenheimer bodies are small aggregates of ferritin. Such debris is normally eliminated by the spleen.

Causes:

  • Post-splenectomy
  • Lead poisoning
  • Sideroblastic anaemia
Pappenheimer Bodies. Peripheral blood film from a patient who had a splenectomy, showing fine peripheral aggregates in the red cells. These are Pappenheimer bodies, and are often easy to miss.
Peripheral blood film from a patient who had a splenectomy, showing fine peripheral aggregates in the red cells. These are Pappenheimer bodies, and are often easy to miss.
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